Try adding the game as a DEP exception, and make sure that you’ve extracted the game when trying to run Game.exe, otherwise the game won’t be able to run properly.
To add a DEP exception:
- Open Control Panel
- Search for Advanced System Settings
- Click the only result (should have a shield icon iirc)
- Go to Advanced
- First option should say Performance, click Settings, this opens a new window
- Go to Data Execution Prevent
- Click the “Add…” button
- Add the game executable
- Press apply/OK, restart the game